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CompARE is a web-platform inspired to provide help on issues relating to trials with composite endpoints. CompARE may be used as a tool for calculating the main elements needed in the planning phase of clinical trials involving composite endpoints.

With its user-friendly interface, CompARE allows to input the main parameters included in the trial -such as the treatment effect on the components of the composite endpoint, and its frequencies of occurrence- and helps provide statistical power and sample size calculations among others.

The main lines of action in CompARE are: (i) sample size calculations under different situations, (ii) implementation of the ARE method for choosing between a composite endpoint or one of its main components as the primary endpoint to lead the trial, (iii) treatment effect specification for the composite endpoint based on marginal information of the composite components. 

Authors: Gómez G, Bofill M, Cortés J

Year of publication: 2013.

Last release and date (dd/mm/yy): 16/02/2018